Oxandrolone – Anavar
Anavar, known scientifically as Oxandrolone, is a mild anabolic steroid favored by athletes and bodybuilders for its ability to promote weight gain without significant side effects.
This steroid is particularly appealing as it does not convert to estrogen, lowering the risk of gynecomastia and reducing water retention compared to other steroids.
Launched nearly 50 years ago in North America, Anavar was originally prescribed for various conditions, including infertility, anemia, and muscle wasting in hospitalized patients. Although its clinical use has dwindled, Anavar offers notable benefits: it remains unconverted to estrogen and minimally affects the hypothalamic-pituitary axis. Consequently, users can avoid common side effects associated with anabolic steroids, such as decreased libido and testicular atrophy.
Pharmacology
Oxandrolone exhibits both anabolic and androgenic properties similar to testosterone. At low doses, it acts primarily as an anabolic agent, while higher doses may elevate its androgenic effects. The steroid can suppress gonadotropin release from the hypothalamus, impacting testosterone synthesis. Like many anabolic steroids, it may adversely affect cholesterol levels, increasing LDL (bad cholesterol) and decreasing HDL (good cholesterol).
Indications
Clinically, Oxandrolone’s use is limited, primarily prescribed for severe cases of malnutrition, trauma recovery, or weight gain post-infection. Although its production ceased in 1989 due to abuse, it is currently manufactured by Savient Pharmaceuticals under the name Oxandrin. Physicians may still prescribe it in select cases.
Dosage
The typical dosage for treating conditions like anemia or aiding weight gain ranges from 2.5-20 mg/day, split into 2-4 doses. Patients may respond variably, with some requiring higher doses up to 150 mg/day. Treatment duration generally spans 3-6 weeks, with gradual increases if necessary. Oxandrolone is available in 2.5 mg and 10 mg tablet forms.
While Oxandrolone is generally well-tolerated, potential side effects can arise, including:
- jaundice
- hepatic necrosis (rare)
- liver cancers
- general malaise
- testicular atrophy
- hair loss
- breast enlargement
- abdominal cramps, nausea, bloating
- acne, oily skin
- diarrhea
- menstrual irregularities
Most side effects tend to resolve upon discontinuation of the drug.
Contraindications
Oxandrolone should be avoided in patients with:
- suspected prostate or breast cancer
- pregnancy
- hypercalcemia
- allergy to anabolic steroids
Bodybuilders
Anavar is a popular choice among bodybuilders due to its effective absorption and minimal side effects at low doses. Most men take one tablet twice daily, while women typically require only one tablet per day. Dosage often begins low and can combine with other steroids like Dianabol, Winstrol, or Anadrol for enhanced results. The typical cycle lasts between 4-8 weeks, starting at 5 mg per day and increasing over time.
Women appreciate Anavar for its minimal virilizing effects; however, exceeding 5 mg daily or prolonging treatment beyond six weeks may lead to masculinization. Weight gain tends to be gradual, with noticeable results within 3-4 weeks.
Signs of virilization include:
- deep voice
- decreased libido
- clitoral enlargement
- acne
- excessive hair growth
Women exhibiting virilization symptoms should discontinue use immediately. While acne and hair growth may revert, some symptoms can be irreversible.
Warnings
Anabolic steroids can damage the liver and may lead to jaundice; serious complications such as liver cancer are possible. Regular liver enzyme tests or annual ultrasounds are advised for those taking Anavar.
Overdose
While overdoses of anabolic steroids are uncommon, misuse of Anavar can lead to discomfort rather than life-threatening issues. Seeking emergency medical assistance is advisable in severe cases, with supportive treatment recommended.
Costs
Anavar’s price for 100 tablets (2.5mg) typically ranges between $100 and $150, but demand has led to widespread counterfeit products. Ensure purchases are made through reputable sources to avoid scams. Authentic Anavar from pharmacies can cost between $700-$1200 for 100 tablets.
Levels
Oxandrolone and its metabolites are detectable in urine, remaining identifiable for 7-14 days post-ingestion. Major sporting organizations conduct regular screenings for anabolic substances.
Legal
As a controlled substance in the USA, Anavar’s sale and distribution are prohibited. The DEA actively monitors its circulation in pharmacies and online. Possession of Anavar without a clinical prescription is considered illegal.
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