Oxandrolone – Anavar
Anavar, a mild anabolic steroid, is favored by athletes and bodybuilders primarily for its effectiveness in promoting weight gain. Its popularity stems from its unique attribute: it does not convert to estrogen, leading to reduced risks of gynecomastia and minimal water retention.
Introduced nearly 50 years ago in North America, Anavar was initially used to treat various infertility disorders, anemias, and weight loss in seriously ill patients. Although its medical applications have diminished over time, Anavar remains notable for two significant benefits compared to other anabolic steroids; it does not convert to estrogen and does not considerably impact the hypothalamic-pituitary axis at low doses, thereby preventing undesirable side effects such as loss of libido or testicular atrophy.
Pharmacology
Oxandrin exhibits properties typical of both anabolic and androgenic medications. At lower doses, it possesses selective anabolic properties while higher doses can trigger pronounced androgenic effects. Excessive doses may reduce gonadotropin release, consequently lowering testosterone synthesis. Additionally, like many anabolic steroids, Oxandrin can negatively influence cholesterol levels, increasing harmful LDL while decreasing beneficial HDL. It stands out as one of the few anabolic steroids that remain non-aromatizing at lower dosages.
Indications
The clinical use of Oxandrolone is sparse today. Historically, it was administered for various anemias, weight loss in HIV patients, and attempted for osteoporosis treatment. Following rampant abuse, Searle halted production in 1989, but Savient Pharmaceuticals now manufactures Oxandrin. Some physicians prescribe it for moribund patients needing to regain weight post-trauma or infection. Occasionally, it is paired with corticosteroids to alleviate bone pain in cancer patients.
Dosage
For therapeutic use in conditions like anemia or weight gain, the adult dosage typically ranges from 2.5 to 20 mg/day, divided into 2 to 4 doses. Individual responses may vary, with some requiring doses as high as 30-150 mg/day. The treatment duration is generally between 3-6 weeks, with progressive increases if no response occurs by week four. Oxandrin is available in tablet forms of 2.5 mg or 10 mg.
As with all anabolic steroids, Oxandrin can produce side effects, mostly mild at lower doses, potentially involving minor abdominal discomfort, nausea, or diarrhea. However, higher doses may lead to more significant issues including:
- jaundice
- rare hepatic necrosis
- liver tumors
- general malaise
- testicular atrophy
- hair loss
- breast enlargement
- stomach cramps, nausea, bloating
- acne, oily skin
- diarrhea
- menstrual irregularities
Most side effects are reversible after discontinuation of the drug.
Contraindications
Oxandrolone should not be administered to individuals with:
- suspected prostate cancer
- breast cancer (male or female)
- pregnancy
- evidence of hypercalcemia
- known allergies to anabolic steroids
Bodybuilders
<pMany bodybuilders utilize Anavar due to its high absorption rate when taken with meals. Typical dosing for men involves one tablet twice daily, while women often only require a single tablet daily. Most bodybuilders commence at a lower dosage, with many combining Anavar with other substances like dianabol, winstrol, or anadriol to minimize side effects. Treatment periods typically last from 4 to 8 weeks, with recommended starting doses around 5 mg daily, gradually increasing over 2-3 weeks.
Women’s preference for Anavar stems from its minimal virilization effects at low doses. However, doses exceeding 5 mg per day or extended treatment beyond 6 weeks may present virilization symptoms, and weight gain tends to manifest gradually over 3-4 weeks.
Potential signs of virilization include:
- deepening voice
- decreased libido
- clitoral enlargement
- acne
- excessive hair growth
Any women exhibiting virilization signs should cease use immediately, as only some symptoms may reverse after stopping the drug.
Warnings
All anabolic steroids, including Anavar, pose a risk of liver damage and jaundice. Cases of liver dysfunction and hepatic tumors have been reported. The most severe complication related to anabolic steroid use is liver cancer, thus individuals using Anavar should maintain awareness of this risk, considering routine liver enzyme evaluations and even annual ultrasounds.
Overdose
Most anabolic steroids, including Anavar, are relatively safe, and overdose scenarios are rare. While excessive consumption may lead to discomfort, it typically is not life-threatening; however, seeking medical advice in these situations is advisable as treatment usually involves supportive care.
Costs
Anavar pricing for 100 tablets (2.5 mg) ranges from $100 to $150. Due to high demand, counterfeit products are prevalent. Buyers must ensure to source Anavar from reputable dealers, as purchasing from unreliable sources may expose them to significant risks. Legitimate Anavar from pharmacies can cost between $700 and $1200 for 100 tablets.
Levels
Anavar and its metabolites can be detected in urine; prominent sports organizations routinely screen for anabolic steroids. Some metabolites may remain in the body for 7-14 days after the last dose.
Legal
Anavar is classified as a controlled substance, making its sale and distribution illegal in the USA. The DEA closely monitors its availability both in pharmacies and online. As Anavar lacks approved clinical use in the USA, personal possession is treated as an offense.
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