Oxandrolone – Anavar
Anavar is a gentle anabolic steroid popular among athletes and bodybuilders, primarily for its weight-gain benefits. Notably, it does not convert to estrogen, reducing the risk of gynecomastia and water retention.
Launched nearly 50 years ago in North America, Anavar was once prescribed for various medical conditions, including infertility disorders and muscle wasting in hospitalized patients. While its clinical use has dwindled today, its key advantages remain: it avoids estrogen conversion and significantly affects minimal hormonal suppression at low dosages. Thus, users can avoid common side effects like loss of libido and testicular atrophy associated with other anabolic steroids.
Pharmacology
Oxandrolone possesses both anabolic and androgenic properties, mirroring the actions of testosterone. At lower doses, it exhibits selective anabolic effects, but at higher doses, androgenic effects increase, potentially leading to hormonal suppression. Additionally, it impacts cholesterol levels, raising harmful LDL cholesterol while lowering beneficial HDL cholesterol. Significantly, Anavar remains unaffected by estrogen conversion at lower dosages.
Indications
Though rarely employed in modern clinical practice, Anavar has historically been used for conditions like anemia and weight loss in HIV patients. Following misuse, production ceased in 1989 but has since resumed by Savient Pharmaceutical under the name Oxandrin. Now, physicians may prescribe it for severely ill patients needing to gain weight post-trauma or serious infections, often along with corticosteroids to alleviate bone pain in cancer patients.
Dosage
Adult dosages for conditions like anemia or weight gain typically range from 2.5 to 20 mg per day, divided into 2-4 doses. Individual responses vary, with some requiring up to 150 mg/day over a therapeutic course of 3-6 weeks, incrementally increasing the dose based on response. Oxandrin is available in 2.5 mg and 10 mg tablet forms.
Like all anabolic steroids, Oxandrolone may lead to side effects. At lower doses, side effects such as abdominal discomfort and mild nausea are common; however, higher doses could result in more severe issues, including:
- Jaundice
- Hepatic necrosis
- Liver cancers
- General malaise
- Testicular atrophy
- Hair loss
- Bloating and stomach cramps
- Acne and oily skin
- Diarrhea
- Menstrual irregularities
Fortunately, most side effects are reversible upon discontinuation of the drug.
Contraindications
Oxandrolone is contraindicated in patients with:
- Suspected prostate cancer
- Breast cancer in either gender
- Pregnancy
- Evident hypercalcemia
- Allergy to anabolic steroids
Bodybuilders
Many bodybuilders favor Anavar due to its swift absorption and minimal side effects when taken with food. Males typically consume one tablet twice daily, while females take one daily. Most athletes start with lower doses, often stacking Anavar with other steroids like Dianabol, Winstrol, or Anadriol. Treatment durations vary from 4-8 weeks, with an initial recommended dose of 5 mg per day, gradually increasing over 2-3 weeks.
It is particularly sought after by women, given its low incidence of virilization at lower doses. However, doses exceeding 5 mg daily or treatments lasting longer than six weeks may lead to signs of masculinization, with gradual weight gain typically noticeable after 3-4 weeks.
Signs of virilization can include:
- Deep voice
- Decreased libido
- Clitoral enlargement
- Acne
- Excessive hair growth
Women experiencing virilizing symptoms should discontinue the drug immediately. While some side effects like acne may reverse, others may not.
Warnings
All anabolic steroids, including Anavar, pose potential risks to liver health, including jaundice and liver dysfunction. The most severe complication can be liver cancer, thus regular liver monitoring through enzyme checks or ultrasounds may be prudent for individuals using this drug.
Overdose
Overdosing on anabolic steroids like Anavar is highly unlikely, as even excessive pill consumption usually doesn’t result in life-threatening consequences. However, seeking emergency medical attention is advisable in such cases, with supportive treatment recommended for any steroid overdose.
Costs
The price for 100 tablets (2.5 mg) of Anavar ranges from $100 to $150, but high demand has fostered counterfeit products. To avoid substandard versions, always purchase from reputable suppliers. Products sourced from Mexico may lack guaranteed quality. Authentic Anavar available through pharmacies typically costs between $700 and $1200 for 100 tablets.
Levels
Both Anavar and its metabolites are detectably present in urine, with major sports organizations screening for anabolic steroids regularly. Metabolites of Anavar could remain detectable for 7-14 days following the last dose.
Legal
Anavar is classified as a controlled substance, making its sale and distribution illegal in the USA. The DEA monitors its availability in pharmacies and online. Since Anavar is not approved for clinical use in the USA, possession is also considered a criminal offense.
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