Oxymetholone – Anadrol
Anadrol (oxymetholone) is a potent synthetic steroid available in tablet form, widely recognized for its anabolic and androgenic properties. This oral anabolic steroid effectively enhances nitrogen balance when combined with a calorie-rich diet. However, similar to testosterone, Anadrol can severely impair sexual and physical development in children, often leading to grotesque physical characteristics and sexual dysfunction.
Pharmacology
Anadrol, marketed as Oxymetholone, boasts a half-life of approximately 8-10 hours, resulting in prolonged retention in the body due to its strong affinity for fatty tissues. According to biochemical analysis, traces of Anadrol can linger in the system for up to two months post-ingestion. Despite its effectiveness, many bodybuilders choose to avoid Anadrol due to its extended half-life, often reserving it for off-season body enhancements.
Indications
In clinical settings, Anadrol is prescribed for various types of anemia, including iron deficiency anemia, aplastic anemias, myelofibrosis, and anemia due to immunosuppressive therapies. It is important to note that it does not serve as a substitute for iron or other essential nutrients and is only used when other treatments are ineffective. Additionally, it may be used for weight loss in HIV patients and severe osteoporosis, but its potential side effects often deter physicians from prescribing it.
Dosage
Anadrol dosage is tailored to body weight, generally ranging from 1.5-2 mg/kg (50-200 mg/week) for both adults and children. Therapeutic responses typically manifest after 2-3 weeks, with some patients requiring a lower dose for optimal effects on aplastic anemias. This steroid is exclusively available in tablet form and is not administered intravenously.
Side Effects
Prior to using Anadrol, it’s essential to understand the range of possible side effects, which include:
- jaundice
- risk of liver cancer
- penile enlargement if taken pre-puberty
- testicular atrophy, reduced sperm count post-puberty
- impotence, painful erections
- in women: clitoral enlargement, menstrual irregularities
- insomnia
- gynecomastia
- voice deepening
- excessive hair growth
- fatigue
- edema
- elevated blood sugar levels
Contraindications
- prostate cancer
- male breast cancer
- female breast cancer
- pregnant women
- individuals with liver disorders
- those allergic to the drug
Bodybuilding
Anadrol is widely utilized amongst athletes and bodybuilders, renowned for its potency and affordability. Easily accessible on the black market, many bodybuilders procure it online or through forged prescriptions, with significant amounts smuggled from Mexico and Thailand. Users typically experience gradual weight gain, often noted within 3-4 weeks. Contrary to claims of rapid results, the drug requires consistent use for at least 3-6 weeks to sustain desired gains. Bodybuilders frequently cycle Anadrol with growth hormone and thyroid medications despite its notorious side effect of water retention, which many believe aids in joint protection.
Furthermore, Anadrol has been reported to enhance recovery speed post-injury. Nonetheless, due to its severe side effects and liver cancer risk, its use is advised to be limited, often replaced with other anabolic steroids during cycles. Recent studies also indicate that prolonged use might lead to unpredictable psychological effects, including increased aggression and irritability. Recommended starting dosages for bodybuilding are around 50 mg daily for 2-3 weeks, with increments to 75 mg if necessary, but it’s crucial to limit usage to 6-8 weeks at a time. Variations like Thai 50 or Strol V are common, yet users must be wary of counterfeit products.
Cost
The pricing for Anadrol is relatively high, with 100 tablets averaging between $150 and $200.
Control
The prevalent misuse of Anadrol has prompted stricter regulations in North America. Classified as a Schedule III controlled substance, it necessitates a physician’s prescription. Possession for distribution purposes can lead to hefty fines and potential imprisonment.
Detection
As a banned substance in sports, Anadrol is routinely tested in athletes. Positive results typically lead to suspensions, with detectable traces persisting in urine for 20-45 days after the last dose.
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