Testosterone Enanthate
Testosterone, the key hormone for male sexual development, is vital for the growth and maintenance of male reproductive organs and secondary sexual characteristics. This androgenic hormone also exhibits anabolic properties, promoting protein synthesis and a favorable nitrogen balance, particularly when paired with a nutritious low-calorie diet.
Additionally, testosterone stimulates erythropoietin (EPO) synthesis leading to an increase in red blood cell production, enhancing oxygen transport capacity.
Long-term use of testosterone can inhibit gonadotropin release from the pituitary gland through a negative feedback loop and may suppress spermatogenesis at elevated dosages.
Dosage
Testosterone enanthate (Delatestryl) is designed for slow dissolution post-intramuscular injection, recommended not more than once or twice a month. The esterified testosterone formulation ensures prolonged action, suspended in colorless to slightly yellow sesame oil. Typical medical dosages range from 250-500 mg monthly.
Indications
Delatestryl is prescribed to address testosterone deficiency conditions, such as:
- Primary hypogonadism (injured testes)
- Hypogonadism due to pituitary gland dysfunction
- Delayed puberty
In women with breast cancer, testosterone can impede estrogen effects and serve as an alternative to ovary removal.
Long-term therapy is often necessary for adequate development of secondary sexual traits in cases of testosterone deficiency.
Duration
The treatment regimen with testosterone enanthate varies based on individual factors like age, sex, diagnosis, and treatment response. This drug is typically well-tolerated when administered correctly. Delatestryl should be injected into gluteal muscles, rotating sites to prevent abscesses, despite the option of thigh injections. Avoid intravenous use.
Do not exceed 1000 mg monthly due to prolonged activity; bi-weekly dosing is uncommon. Always inspect the drug prior to injection, ensuring it’s clear and without clumps or particulate matter. Treatment duration generally spans 4-6 months.
Store the drug at room temperature.
Bodybuilders
Many bodybuilders incorporate Delatestryl during off-season training, appreciating its long-lasting effects, while cautioning against use during competitive seasons. Though it possesses notable anabolic and androgenic properties, visible effects may require 3-4 weeks. Some athletes use it in conjunction with other hormones like GH/thyroxine.
Due to testosterone’s conversion to estrogen in adipose tissue, it’s common to experience water retention or breast enlargement. Doses for muscle growth typically range from 250-1000 mg/week. Beginners are advised to start with lower amounts to mitigate strong side effects.
The gradual protein mass increase is notable, alongside enhanced performance under rigorous training, marking testosterone enanthate as a preferred choice among bodybuilders. Reports of fat reduction and muscle gain persist, with minimal detection in urine within initial weeks. However, water retention may necessitate diuretic use, while cycles often involve medications like Arimidex or Tamoxifen to manage breast enlargement, following a 4-6 week intake period.
Women
All testosterone analogues can trigger virilizing effects in women with extended use. Symptoms may include deepening voice, excessive hair growth, menstrual irregularities, mood changes, and clitoral enlargement. Immediate cessation is recommended upon noticing any virilizing signs, as some effects may be irreversible.
Side Effects
As with all anabolic steroids, testosterone enanthate presents mild side effects well-tolerated by most users, typically showing after 3-4 months of therapy. Common side effects include:
- Irregular bleeding
- Virilizing effects
- Voice deepening
- Clitoral enlargement
- Gynecomastia
- Painful erections
- Hair loss, acne, oily skin
- Water retention
- Nausea, vomiting, jaundice
- Liver cancer (rare)
- Mood alterations, depression, headaches, anxiety
- Elevated serum cholesterol
While most side effects can reverse, breast enlargement and some virilizing effects may not. Concurrent estrogen use for mitigating virilization effects is often ineffective.
Child usage must be carefully monitored due to potential early bone maturation without proportional linear growth, risking skeletal anomalies.
Warnings
Exercise caution when using testosterone in individuals with:
- Breast cancer and hypercalcemia
- Liver dysfunction
- Prostate cancer
- Cardiac issues
Some users have reported respiratory difficulties, potentially linked to the drug’s oil preparation or impurities in formulation.
Regular monitoring of liver functions and blood hematocrit is crucial for all testosterone users to ensure safety.
Recognition
Testosterone enanthate’s long half-life enables detection in urine well after cessation, often identified 3-4 weeks post-use. Advanced testing now extends to hair samples, revealing traces for 2-4 months following discontinuation, though accuracy may be hampered by ratios of testosterone to epitestosterone in about 50% of users.
Cost
Legal access to testosterone enanthate can be challenging, leading most bodybuilders to obtain it from black market sources. Generic versions are readily available in Europe and Mexico, usually priced between $10-$20 for a 250 mg vial. Increased regulatory scrutiny by the DEA has led to counterfeit products, making caution essential for buyers.
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