Oxandrolone – Anavar
Anavar, known scientifically as Oxandrolone, is a popular mild anabolic steroid favored by athletes and bodybuilders seeking to enhance weight gain. Its appeal lies in its unique ability to remain free from conversion to estrogen, thus reducing the risk of gynecomastia and promoting minimal water retention.
Introduced to the North American market nearly 50 years ago, Anavar initially served various medical purposes, including treatment for infertility disorders and weight loss in hospitalized patients. Today, its clinical application has diminished, but Anavar remains a preferred anabolic option due to two key advantages: it doesn’t convert to estrogen and has little effect on the hypothalamic-pituitary axis. Consequently, users can avoid common steroid-related side effects like reduced libido and testicular atrophy.
Pharmacology
Oxandrin exhibits both anabolic and androgenic properties; at low doses, it selectively promotes anabolism, while higher doses can trigger potent androgenic effects. Elevated doses may lead to suppressed gonadotropin release, consequently lowering testosterone production. Like most steroids, Oxandrin increases LDL cholesterol levels while decreasing HDL cholesterol, however, it is notable for not converting to estrogen at lower doses.
Indications
Although infrequently prescribed today, Anavar was historically utilized for various medical conditions such as anemias and significant weight loss in HIV patients. Following widespread abuse, production ceased in 1989 by Searle, but Savient Pharmaceuticals now markets Oxandrin. Some physicians still prescribe it for weight gain in critically ill patients post-trauma or burns, often paired with corticosteroids for pain relief in cancer treatment.
Dosage
The recommended dosage for adults aiming to counter anemia or promote weight gain ranges from 2.5-20 mg/day, usually divided into 2-4 doses. Individual responses vary, with dosages between 30-150 mg/day sometimes necessary. Treatment typically lasts 3-6 weeks with gradual increases where needed. Oxandrin is available in 2.5 mg and 10 mg tablet forms.
As with any anabolic steroid, Oxandrin comes with potential side effects. At low doses, risks are generally mild, including abdominal discomfort, nausea, or diarrhea. At higher doses, more severe effects can manifest:
- jaundice
- rare hepatic necrosis
- liver cancers
- general malaise
- testicular atrophy
- hair loss
- breast enlargement
- abdominal cramps, nausea, bloating
- acne, oily skin
- diarrhea
- menstrual irregularities
- testicular atrophy
Most side effects are reversible upon discontinuation of the drug.
Contraindications
Oxandrolone should be avoided in patients with:
- suspected prostate cancer
- breast cancer (male or female)
- pregnancy
- evidence of hypercalcemia
- allergy to anabolic steroids
Bodybuilders
Anavar is highly regarded among bodybuilders due to its rapid absorption. Recommended dosages are typically one tablet twice daily for men and one tablet daily for women, with initial doses starting low to minimize side effects. Many athletes stack Anavar with other steroids such as Dianabol, Winstrol, and Anadrol. Typical cycles last 4-8 weeks, with most experts advising a start at 5 mg/day, increasing gradually over 2-3 weeks.
This steroid is especially popular among women because it produces minimal virilizing effects at lower doses. However, exceeding 5 mg daily for over 6 weeks may result in signs of masculinization. Users can expect gradual weight gain, often noticeable after 3-4 weeks.
Signs of virilization may include:
- deep voice
- decreased libido
- clitoral enlargement
- acne
- excessive hair growth
If virilization occurs, women should discontinue use immediately, as some changes may not be reversible.
Warnings
All anabolic steroids, including Anavar, carry a risk of liver damage and jaundice. Serious conditions such as liver dysfunction and carcinoma have been reported. Regular monitoring of liver enzymes and annual ultrasounds are advisable for those under treatment.
Overdose
Although unlikely, steroid overdose is possible and while not life-threatening, it may cause discomfort. Immediate medical attention is recommended in such cases. Treatment primarily involves supportive care.
Costs
The price of Anavar (100 tablets of 2.5 mg) ranges from $100-$150. However, due to high demand, counterfeit versions are prevalent. Purchasing from reputable sources is crucial, particularly as personal possession of Anavar is illegal in the USA.
Levels
Anavar is detectable in urine, with metabolites often persisting for 7-14 days post-use. Major sports organizations routinely test for anabolic steroids, ensuring compliance with anti-doping regulations.
Legal
As a controlled substance, the sale and distribution of Anavar are prohibited in the USA. The DEA actively monitors its availability in pharmacies and online, rendering personal possession a criminal offense.
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