Dapoxetine
Dapoxetine is a clinically approved treatment for premature ejaculation in men, marketed under the brand name Priligy.
Mechanism of Action
- Dapoxetine is classified as a selective serotonin reuptake inhibitor (SSRI).
- This medication enhances serotonin availability in the brain by slowing its reuptake.
- Higher serotonin levels help improve ejaculation control, allowing for extended duration before climax.
Indications
- Primarily effective in treating premature ejaculation in males.
- Recommended for men aged 18 to 64 experiencing rapid ejaculation issues.
Onset of Action
- Dapoxetine exhibits a quick onset, typically within 1 to 2 hours post-administration.
Duration of Action
- Effects generally last between 4 to 24 hours, varying by dosage and individual response.
Dosage
- Standard dose ranges from 30 mg to 60 mg as required.
- Starting dose is usually 30 mg, with potential adjustments based on patient response.
Side Effects
- Common side effects may include dizziness, headache, nausea, drowsiness, fatigue, and dry mouth.
- Infrequent side effects can involve hot flashes, heightened nervousness, behavioral alterations, or sexual function changes.
Contraindications
- Not suitable for individuals with severe hepatic or renal impairment, significant cardiovascular issues, epilepsy, bipolar disorder, or those taking MAO inhibitors.
- Combining dapoxetine with alcohol should be avoided due to an increased risk of adverse effects.
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